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An enzyme that breaks down a substance in the body called hyaluronic acid. Hyaluronic acid is found throughout the body in connective tissue, skin, and fluids in the joints and inside the eye. It causes fluids to have a jelly-like thickness, which can help moisten and protect tissues and joints. In medicine, hyaluronidase is made in the laboratory and given with other drugs by injection under the skin to treat certain conditions. Using hyaluronidase to break down hyaluronic acid helps make the fluids and connective tissue thinner so the drugs can move more easily into the tissues.

How does Hyaluronidase Work?

Hyaluronidase works as an enzyme to temporarily break down hyaluronic acid which is found naturally in the body. This makes it easier for injection of fluids to be administered, and effective absorption of the fluids into the skin and tissue.

Hyaluronidase additionally aids the body to  reabsorb blood and fluids from the tissues, in the case of a large bruise.

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  • Aid in the penetration of fluids during subcutaneous and intramuscular injections
  • Hyaluronidase can be directly added to the fluid or solution that is being infected into the skin
  • Aids absorption of a subcutaneous infusion, where Hyaluronidase is injected beforehand into the site of injection where the injection is to be administered
  • To aid the body to reabsorb fluids or blood in haematomas or extravasation, where Hyaluronidase is mixed with saline or water before being injected at the site of injection
  • Breaks down Hyaluronic acid which is present between cells to help them adhesive together. This is a temporary action and helps the quick absorption of fluid injections.
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